Autoimmune Liver Disease Symptoms

Liver disease is categorized both by the cause and the effect it has on the liver. Causes may take in infection, injury, exposure to drugs or toxic compounds, an autoimmune process, or a genetic defect. These causes can lead to hepatitis, cirrhosis, stones that develop and form blockages, fatty liver, and in rare instances liver cancer. Genetic defects can prevent vital liver function and lead to the deposition and build-up of damaging substances such as iron or copper.

Liver disease is a broad term that covers all the potential problems that may occur to cause the liver to fail to perform its chosen functions. Usually, more than 75% or three quarters of liver tissue needs to be affected before decrease in function occurs.

Symptoms of Liver Disease: -

a See if the patient has discoloration of skin. The skin and eyes acquire a yellowish tinge and the urine turns dark yellow. It is called jaundice and this is considered to be the primary sign of liver disease. a Check for light colored stools as it indicates the beginning of liver disorder. A liver patient may also complain of irritable bowels or irregular bowel movements.
a Find out if there is distended abdomen. Swelling under the right lower ribs is a common complaint of liver patients. It can put severe pressure on the diaphragm that results in painful breathing.
a Examine the shape and appearance of the nails. Curved and whitish look of nails also suggests a liver problem.
a Notice nose bleeding and easy bruises as it shows liver abnormality and deficiency of proteins.
a Frequent headaches, dizziness, spasms, irritability, depression and so on are also indicative of liver problem.

Liver Disease Treatment: –

a Add a little salt and some roasted cumin seeds to a glass of buttermilk. Drink this early in the morning. This will keep your liver healthy and protects it from disorders.
a Decrease fat intake by 20-30 grams per day as in liver damage, bile secretion and digestion is affected that hinders the fat absorption.
a Fatty liver, also known as statuses, is an accumulation of fat in the liver that typically does not cause liver damage.
a Take small meals as they are easily digested and create less trouble for liver functioning. Do not eat deep fried refined flour products as they harm your liver and its functioning.
a For liver problem, detoxification of the liver is necessary. This is done by fasting for a day. After that, food that is easy to digest must be taken. Bitter vegetables such as bitter gourd and bitter drumstick must be given.
a Keep a white-colored glass bottle filled with water in the sun for 6-8 hours and drink it after cooling. This is a very simple home remedies for liver cirrhosis.

Frequently Asked Questions

    Do I possibly have leukemia or some other blood disease? ADVICE FROM EXPERIENCED/ or DOCS?
    my symptoms are, and noted beggining about a year ago, disapearing and reapearing regulary but not serious, but recently symptoms have returned elevated and much more serious then past experiences, symptoms include…

    bleeding gums, paleness, red dots on skin that are itchy, patchy red palms,, white fingernails under nail, yellowing at tip of fingures, fatigue, joint pain. wrestlessness, trouble waking up. (sleep long hours) sometimes bed at 8pm and up at 4-6pm the next day. and swallen lymph nodes in my lower neck and under my jaw…. (SINCE THIS NIGHT I HAVE DEVELOPED BUMPS UNDER MY LEFT ARMPIT AND CHEST PAIN) I also am beggining to feel ill, feels like the flu, but rather strange as my headache will go and come back in a different area…

    Here is my doctors summary from saturday night. when i attended the emergancy dept…

    (Jaime Waters presented to Box Hill hospital Emergancy Department on 07 Aug 2010 at 15:40

    ED Diagnosis: Bleeding disorder for investagation
    History of presenting Complaint: 20 y.o male presented with 2 month histroy of bleeding gum and joint pain with no significant background histroy.

    Patient first noticed gum bleeding at least 3 or more months ago after brushing, since then bleeding has become more consistant, bleeding lasting now upto 10 minuts after brushing. also noticed incease of joint pain mainly on MCP joint and knee joints over this period of time.

    Bleeding has worsened over the past 5 days and become consistant in the past 2 days. patient now also complains of lethargy and weakness in this time frame.

    smoker since 14

    heavy drinker; usually 2-4 bottles a week.
    Last alcohol yesterday 1/2 bottle bourben.

    No family history of bleeding disorder, auto immune disease or leukemia.

    Resting tremor noted, no heptic flap, no obvious brusing/petechae
    No sign of chronic liver disease
    No conjuctiva pallor, no scleral jaundice

    chest clear
    abdo soft tender, no oragomegaly

    Oral examination – no active gum bleeding, no obvious gingervitis, tonsil not enlarged.

    tender submental lymph node bilaterally R>L
    Palpable R cervical lymph nodes
    Thyroid not enlarged

    stiffness of mcp joint both hands no tenderness on palpation and movement

    Managment: FBE/U+E/Coags/LFT/CRP
    may need medical refferal for bleeding disorder

    Results/outcome: Neutrophilia and increase WCC
    Normal LFT and Coagulation profile hb166

    Refferals and followup: Need LMO follow up for investagation of autoimmune disease and thrombolic screening,

    patient wil need new LMO for follow up and observation of progression.)

    in this letter not all my symptoms are noted. but i hav put as much as i can think of before i added this letter, also the doctor told me im developing a little bit of anemia but was nothing to be concerned about at this time and that i needed to be observed over the next few weeks for a diagnosis of whats happening. and refferd me to a GP.

    can anyone offer me advice?

    since seeing the doctor my under left armpit has become sore and stiff, my left hip bone upper left beg bone has began to ache with worsening bleeding of gums. and consistant taste of blood in mouth. im very confused and worried about whats goin on… advice?

    • ANSWER:
      When you go to that referral, ask them to test you for Lyme’s disease. I have a friend with similar symptoms and it turned out to be Lyme’s disease. Have you been camping or in the woods lately? Even if you haven’t, deer tics can be in tall grass and you don’t even know they are on you. It doesn’t sound like cancer to me
      I hope you find out what this is. Be well

    What kind of specialist should I see for the following symptoms:?
    I’ve had the following symptoms for a while now. My general practitioner isn’t cutting it, and I’ve been negative so far for thyroid (hyper and hypo) problems, lupus, fatty liver disease, and diabetes. I’m at the end of my rope. If there is ANYONE out there who has similar symptoms and got help, can you please point me in the right direction?

    Severe Eczema (Since Birth, better with age, worse in winter)
    Severe allergies (Since Birth) (to food like fruits, veggies, and seafood. Meds like penicillin and sulfa, lots of different trees and plants, latex, and pet dander)
    Stunted height (grew very slowly, only 5’2″)
    Rapid weight gain, inability to lose weight with proper diet and exercise (since my teens)
    Depression, and generalized anxiety disorder (Since my teens, worsens as I age. GAD was misdiagnosed as major depressive disorder for a long time)
    Migraines (intermittent, started in my teens)
    Fatigue (10+ hours of sleep per night)
    Gastrointestinal (I’ve always had constant gas. I get diarrhea very easily. Stomach aches give me severe headaches and will make me vomit)
    Insulin resistance (recently diagnosed)

    For a while, my thinking was that the depression and anxiety was causing an inability to deal with stress, which in turn caused the weight gain, and fatigue, and made my allergies/eczema worse. Then I couldn’t lose weight for the life of me, and since my family has a history of autoimmune disorders, that led to the thyroid testing. Now I’m getting this insulin problem, and my doctor is telling me that I need to lose weight or risk becoming diabetic. But I still can’t lose weight. See the conundrum? The most recent suggestion is that I might have celiac disease, but I looked it up and it seems to mainly have gastrointestinal symptoms, which I have very little of (just the persistent gas, really)

    Anyone have a suggestion? Anyone?

    I’ve had my thyroid checked. Also seen a rheumatologist (had joint pain for a while, but it was chalked up to the rapid weight gain). I also see my allergist and dermatologist regularly, they’ve been the same doctors since birth.

    I thought the allergies and eczema were just hereditary conditions unrelated to anything else until it was recently suggested that I include them in my list of symptoms to see if it narrows down my search, because apparently allergies and eczema can often indicate other disorders.

    • ANSWER:
      An Immunologist would test you to find out exactly what foods and other factors you are allergic to and therefore do not eat or avoid.

      An Endocrinologist would check your thyroid out really well and also advise you about the insulin problem.

      A specialist in Bariatric Medicine is the type of doctor who treats obesity. They use dietary/lifestyle changes and exercises and sometimes medicine in their treatment options.

      However before you contact any of them why don’t you read this book extract in Google Books :

      ” The Inflammation Cure”, by William Joel Meggs, an Immunologist in America. Chapter 9 is the chapter that deals with dietary factors.

      Dr Meggs recommendations are :

      *to NOT eat wheat (found in breads, packet cereals, prepared sauces etc, cakes and biscuits). Doing this alone will stop the wind problem and start you losing weight. Alternatives to wheat are rye crackers, rye bread, spelt bread etc; oats for breakfast cereal.

      * DO NOT have dairy products except maybe pot set natural yoghurt which has beneficial bacteria for easy digestion. Alternatives to cows milk – goat milk, water or soy milk.

      * Lean red meat – beef as it is the best source of protein and iron. Once a week.

      *Oily fish for protein and Omega 3 Oils

      * Approved fruits and vegetables that YOU are NOT allergic or intolerant too.

      *Nuts and seeds that YOU are NOT allergic or intolerant to.

      *No junk food, no bought preprocessed foods.

      Good luck

    What is left for me to say…..?
    I typed up a report on diabetes, it is supposed to be 6 pages dubble spaced, but now i don’t know what else to put, all i need is a half a page more. Thank you!

    Diabetes Type 1
    Diabetes is a disease in which blood glucose levels are above normal. People with diabetes have problems using food for energy. After a meal, carbohydrates in food are broken down into a sugar called glucose, which is carried by the blood to cells throughout the body. Cells require insulin, a hormone made in the pancreas, to help use blood glucose for energy. People develop diabetes because the pancreas does not make enough insulin or because the cells in the muscles, liver, and fat do not respond to insulin properly, or both. As a result, the amount of glucose in the blood increases while the cells are starved of energy.
    Prior to 1997, the type of diabetes typically diagnosed in young people was called juvenile diabetes or type 1. Diabetes emerging in adults was called adult-onset diabetes or type 2. Then in 1997, the official names of the types were changed to type 1 and type 2. Type 1 diabetes is the second most common chronic disease in children (after asthma). About 13,000 new cases are diagnosed in the U.S. each year. Patients with type 1 diabetes make up about 5 percent of all cases of diabetes. It most commonly appears in girls and boys when they are about 14 years old. Usually, type 1 diabetes is first diagnosed in children, teenagers, or young adults but it can occur at any age. Type 1 diabetes is an autoimmune disease in which the immune system attacks the beta cells in the pancreas that make insulin. As a result, the pancreas does not make insulin, a hormone which helps use blood sugar (glucose) for energy. The cells become starved of energy and there is an excess of glucose in the blood. People with Type 1 diabetes must have daily injections of insulin to live. Proper diet, exercise and home blood sugar monitoring are essential to manage the disease. Food and exercise must also be balanced because of the risk of hypoglycemia, low blood sugar, and hyperglycemia, high blood sugar. Both are life threatening concerns. When hypoglycemia develops, cells are not getting enough glucose. Confusion, loss of consciousness, comma and death results when the brain is deprived of glucose for too long. Hyperglycemia and prolonged absence of insulin may lead to ketoacidosis, the accumulation of ketones in the blood when the body uses fat for energy instead of glucose. Ketones make the blood acidic and slow down all body functions. Like hypoglycemia, hyperglycemia can also lead to comma and death. The only cure available today for type 1 diabetes is a pancreas transplant, which is rarely done. Because both pancreas transplants and kidney transplants require lifelong use of powerful drugs to suppress immune reactions that can reject the organs, pancreatic transplants are usually done to those with type 1 diabetes who also need a kidney transplant. The side effects of immune- suppressive drugs can be severe and even worse than the disease. One or two people out of every 10 who get the surgery die within a year. Also the new pancreas is rejected by half of the people who get this operation. If the transplant fails, diabetes returns. Recently, experimental treatments with stem cells have shown some promise. For most people, type 1 diabetes is a life-long disease that can be effectively managed with insulin.

    Signs and Symptoms of Type 1 Diabetes
    •Urinates frequently. The kidneys respond to high levels of glucose in the bloodstream by flushing out the extra glucose in urine. A child with diabetes needs to urinate more frequently and in larger volumes.
    •Is abnormally thirsty. Because the child is loosing so much fluid from peeing so much, he or she becomes very thirsty to help avoid becoming dehydrated. A child who has developed diabetes drinks a lot in an attempt to keep the level of body water normal.
    •Loses weight. (or fails to gain weight as he or she grows) in spite of a good appetite. Kids and teens who develop type 1 diabetes may have an increased appetite, but often lose weight. This is because the body breaks down muscle and stored fat in an attempt the provide fuel to the hungry cells.
    •Often feels tired. Because the body can’t use glucose for energy properly.

    But in some cases, other symptoms may be the signal that something is wrong. Sometimes the first sign of diabetes is bedwetting in a child who has been dry at night. The possibility of diabetes should also be suspected if a vaginal yeast infection (also called a Candida infection) occurs in a girl who hasn’t started puberty yet. If these early symptoms of diabetes aren’t recognized and treatment isn’t started, chemicals called ketones can build up in the child’s blood and cause stomach pain, nausea, vomiting, fruity- smelling breath, breathing problems; even loss of consciousness. Sometimes these symptoms are mistaken f

    • ANSWER:
      Watch out on using advice from yahoo answers if truthfulness is graded. While 80% of type 2′s are overweight, only 18% of obese people are diabetic.

    AND can herpes on your face look like acne, and not be near your mouth?
    im breaking out so bad! and im back on my acne medication which usually clears it up to like 90%!! i have mountain types of red painfull bumps(that dont pop like mine usually do) in all areas on my dermatologist says normal! and a few blisters types.
    BUT my dr’s and i have been doing all kinds of blood, urine and stool tests to figure out whats wrong w/ me because i have been quite sick W/ a ridiculous amount of symptoms……. my symptoms include(but not limited to): extreme weight loss(20%) over the past 7 months w/ no known reason, memory loss,fatigue,confusion, trouble finding words, constipation,blood clots in stool, extreme amount of mucus in stool, malabsorbtion,constant feeling of needing to move bowels, itchy scalp,dry hair and skin, dry mouth, large amounts of yeast in mouth, swollen tender glands throughout entire body(HARD IMMOBILE SLOW GROWING LYMPH NODES IN GROIN ABOUT 1MONTH NOW -now about 1cm-1in big), circulation changes(pigmentation in skin either very pale or red, varicoses veins pronounced in legs when im doing anything physically demanding,broken blood vessels appearing easily; eyes and nose)cold feet and hands, hot flashes(im 29YRS OLD!), pain(inside of knees, lower back, stiff neck, headaches), hands wrists ankles and feet swelling(bilaterally) w/ tingling sensation and numbness, muscle cramping and spams, few BLISTER TYPE canker sores, hair loss, dry eyes, abdominal swelling, appetite up and down but always feeling full quickly, excessive gas, ocd symptoms, behavior changes, THROAT feels full, itchy wet ears(get clogged alot), cuts on fingers and hands slow to heal, allergy type symptoms out of no-where, skin tag inside anus almost at edge, slight vaginal discharge(not strong odor) and swelling(looks as if the walls of vagina are closing in! swollen and low), bump on cervix(that has been there years but now growing fast and a new one just inside opening-purplish in color. i can see it bc cervix is so low and maybe swollen(2gynecologists examined me and said look normal!)
    I HAVE HASHIMOTO DISEASE(autoimmune low thyroid) I HAD A VERY LARGE TUMOR REMOVED FROM CHEST 15 YRS AGO(attached to my trachea,aorta,heart,esophagus and windpipe. but seems to not have grown back according to x rays
    im thinking i have a number of different problems and that’s whats confusing the dr’s-
    i had clear x chest x rays and only one abnormal ekg out of 3(Dr’s say no concern and no found heart probs) clear ultrasound of liver,heart,gall bladder, etc, all basic blood urine and stool tests plus extra thyroid tests, rheumatoid arthritis,lyme disease, celiac, HIV, gonorrhea, chlamydiae, and parasite tests and more.—— all normal so far! (w/ the exception of a slightly low sugar)
    *** im concerned my white blood cell counts are not showing up on tests accurately bc i must have SOME type of infection! LYMPHOMA, CANCER, HIV(that is not showing on test) BRAIN TUMOR! I DONT KNOW-SYPMTOMS ARE SO ALL OVER THE MAP!
    im stressed from all this worrying prb making my sypmtoms more severe and multiply, but i know something is wrong! SOMEONE ANYONE PLEASE HELP ME im seeing dr tom so hopefully some news(GOOD OR BAD AT THIS POINT IS GOOD TO ME!)

    • ANSWER:
      many of those symptoms lead to HIV, and it is not uncommon to have a negative test result when you are actually HIV positive. get retested.. but overall sounds like you just named everything you could think of.

      -vaginal discharge: normal
      -skin tags: normal
      -sores: possible STD
      - bump on cervix: might actually be the cervix, if you gyno can’t see it, im sure it’s fine
      - etc..

      start thinking about what’s changed recently versus worrying so much about the little things. that’s what confuses doctors, when you talk about 100 different things when really the worst symptom is the cause of everything else

      your thyroid problem is most likely causing your lymph nodes to be swollen, as well as most of the symptoms above

      as for the acne.. it is stress induced.. and you seem to be very stressed.

      i suggest stop taking so much medications, consult more doctors until you’re satisfied, they know what your blood work reveals, not us

    I need a diagnosis – severe body pain, low grade fevers, sore stomach, etc.?
    I need help! My doctor can’t diagnose me and I’m in so much pain I don’t know what to do. Starting about a month ago I’ve been getting low grade fevers on and off. It happened a month ago for two days and came with body aches that started in my neck and spread throughout my body. It lasted for two days with no other symptoms and went away completely. A month later I started getting mild to moderate body aches mostly in my arms and legs. It lasted for about a week with low grade fevers again (around 99.7). Now, starting two days ago, I’ve had such severe body aches I can barely move and walk. My neck, back, knees, legs, feet, arms, hands, even my fingers and toes are unbearably sore. I can’t even sit comfortably. It hurts even just typing this.

    This is the main problem (the severe pain) but I also have a sore stomach. Not nausea, not “sick” just sore. Like, it’s sore to the touch, I can’t even push on it. Today for example I was lying on my back and put a book down on my stomach. The pressure from a small, light book was so excruciating I actually gasped and had to take it off. I really think my organs must be inflamed!

    Last but not least I’ve been experiencing Raynaud’s Syndrome. For those of you who aren’t familiar with it, it’s when your fingers and toes go completely white and numb, usually from cold. I haven’t been cold but it happens to me whenever I apply pressure to my fingers – like writing with a pen, using silverware, etc. This has never ever happened to me in my entire life and now it happens 10+ times a day and it all started at the same time as my other symptoms so I think they may be related.

    Here’s what I DONT have (I just got some bloodwork done):
    No autoimmune diseases, no HIV, no vitamin deficiencies

    The only thing that was abnormal on my entire bloodwork is that my liver enzymes are high. My doctor thinks this may be due to long-term use of Minocycline (an antibiotic I’ve been taking for 3 months to clear up my skin). A lot of my symptoms seem like they could be an adverse reaction to minocycline but it just feels like it all came on so suddenly and so aggressively that I don’t know if this can be right and I want some other ideas.

    Can anyone help?? I’m in so much pain I don’t know what to do! And I can’t even take painkillers because of the liver issue (I’m getting an ultrasound of my liver soon).

    Thank you for any help you can give!!!
    Thanks, unfortunately it can’t be any of those things… my doctor tested me for all auto-immune diseases and I have none of them…

    Any other ideas anyone?

    • ANSWER:
      This does actually sound like an auto immune disease. Raynaud’s phenomenon is commonly associated with auto immune diseases. Connective tissue disorders are an immune system response attacking your own connective tissue and causing inflammation that damages your collagen and elastin. There are other conditions associated with Raynaud’s phenomenon as listed below. :)

      Connective tissue disorders:

      Other conditions associated with Raynaud’s phenomenon:

    My LYMPH NODES are extremely palpable (for years) i have lost TOO MUCH WEIGHT, what is wrong?
    Hello….if anyone would like to try to DIAGNOSE ME, I’d be SO GRATEFUL AT THIS POINT!
    ….. i’m 30 year old female, with a 10 year old son and had a thoracic fore gut tumor(benign) removed from my chest @ 15, a good portion of which was attached to my lungs, aorta,esophagus, Trachea.
    To Date- no known complications or regrowth.
    109 lbs
    hypothyroid, on synthroid
    Had IUD recently placed in cervix
    amphetamine salts,celexa, lorazapam for depression/fatigue and ADD
    CURRANTLY AND THIS PAST YEAR: Generalized Swollen lymph glands(some firm and hard in groin area. Also where my hairline is in the back of my neck behind my ear i guess, and a few large ones up the side of my neck aligned with my shoulder), Re currant low Grade Fever(no higher than 101 w/out infection),Itchy Skin, Memory Loss,Hair loss, Acne,Bowel Changes,On and Off fatigue, mucus in my stool(for one year at least.More mucus than actual stool on average! SORRY TO BE SO GRAPHIC! Lower Back Pain, DULL ACHING PAIN on the inside of my knees,stiff neck,ankle pain after being on my feet for more than an hour.Also extremely dry; mouth,skin,hair,eyes,&nostrils, dizziness upon standing, sweats,wounds heal slowly, weird painless swelling above my butt where my dimples are(no dr has been able to guess why/what this swelling might be),diarrhea and constipation, tenderness above my belly button, hyper pigmentation on abdomen, arms and feet, anxiety, blood pressure has steadily increased throughout all of my many dr’s visits this past yr.
    ADDED RECENT SYMPTOMS:Kidney pain, visible blood in urine: for 2 months now! it was bright red and then less visible for awhile and now dark brown like tea and extremely strong smelling, hardening and bloating of abdomen, extreme fatigue, productive cough, chest pain, neck pain,easily exhausted, unexplainable bruises, muscle spasms and bulging type pain JUST under my rib on both sides separately, weird stabbing pain on my left groin area near my larger lymph glands that makes my tendon look swollen, thrush, protein in urine, HI albumin in urine, repetitive rbc in urine, BUT NO INFECTION!! (multiple negative cultures), kidney stone shows on CT in an area that is expected to be asymptomatic and may not even pass. BUT I DO HAVE difficulty urinating and cramping JUST PRESCRIBED CIPRO FOR A SECOND TREATMENT. (not sure exactly why since culture is consistantly negative)

    Many tests HAVE BEEN DONE: …..All Basics(CB C’s, liver, etc panels) + Lyme Disease,Hep(B,C etc), ANA,Sed Rate,R.F.,AIDS, Celiac Disease,Fecal Bacterial+Viral cultures,Lupus,Syphilis, Gonorrhea, Chlamydiae,Anemia, scleroderma, h. pylori, bladder cancer,
    P.C.P. says: hematologist &will do allergy & routine testing upon insurance ok
    E.N.T(ear,Nose&throat) says: inflammation or irritation down deep in my throat(but i smoke so…)
    GASTROENTROLOGIST says: gastritis, hemorrhoids,IBS, lymphoid aggragates in non lymph areas
    UROLOGIST says: extreme gross & microscopic unexplained hematuria, referral to hematologist(concerned about enlarged lymph’s in groin and unexplained hematuria———says kidney stone most likely not causing this amount of rbc,did FISH URINE TEST…NO CALL SO I’M GUESSING ALL CLEAR ON RESULTS)
    HEMATOLOGIST says: i’m thin so nodes are more palpable s we should wait. does not believe biopsy is neccessary at this point
    RHUEHEMATOLOGIST says: no signs autoimmune, non arthritic/ lupus like disease
    GYNOGYNECOLOGIST says: no infection, no discharge see urologist…
    DERMOTOLOGIST says: see rhuemotologist! lol, biopsied pigmented marks(inconclusive-possibe allergic reaction)

    i am waiting on results of a chest CT from HEMATOLOGIST because he heard alot in my lungs and another aids test(that’ll be 4 tests in the last yr(all negative)

    but i can’t remember everything! lol any EDUCATED ADVICE would be appreciated
    THANK YOU!!!! i feel so helpless when i am sooo tired or weak….. i just want a solution!

    • ANSWER:
      See what the CT results are. If you get no answers there, I would go to a different hematologist and insist on a biopsy. If you can’t get answers switch to a hospital that specializes in diagnostics.

    Hepatitis B questions!?
    Hepatitis B:

    •What is the infectious agent? What type of organism is it? What is known about its structure?
    •How does the infectious agent interact with the body to produce symptoms?
    •What cells or tissues does it infect and how does it damage those cells or tissues?

    Infectious agent: Hepatitis B infection is caused by the hepatitis B virus. Hepatitis B virus is present in the blood and body fluids of infected persons.
    Hepatitis B virus (HBV) is a member of the Hepadnavirus family. The virus particle, (virion) consists of an outer lipid envelope and an icosahedral nucleocapsid core composed of protein. The nucleocapsid encloses the viral DNA and a DNA polymerase that has reverse transcriptase activity. The outer envelope contains embedded proteins which are involved in viral binding of, and entry into, susceptible cells. The virus is one of the smallest enveloped animal viruses with a virion diameter of 42nm, but pleomorphic forms exist, including filamentous and spherical bodies lacking a core. These particles are not infectious and are composed of the lipid and protein that forms part of the surface of the virion, which is called the surface antigen (HBsAg), and is produced in excess during the life cycle of the virus.
    A group of viruses known as the hepatitis viruses cause most cases of liver damage worldwide. Hepatitis can also be due to toxins (notably alcohol), other infections or from autoimmune process. It may run a subclinical course when the affected person may not feel ill. The patient becomes unwell and symptomatic when the disease impairs liver functions that include, among other things, removal of harmful substances, regulation of blood composition, and production of bile to help digestion.
    The genome of HBV is made of circular DNA, but it is unusual because the DNA is not fully double-stranded.

    • ANSWER:
      Don’t you think perhaps it would be better if you read the paragraph yourself and answered the questions yourself? I hope this isn’t for nursing school, or something to prepare you for a career in the medical field. I’d hate to think you planned to play with people’s lives and are too lazy to read a short paragraph and answer three questions that can be found so easily by doing so.

    Who can be my Dr. House? I have a mystery illness…?
    I will make this as short as possible. I am a 26 yr old female, in good shape and eat well. Ive had my gallbladder and appendix out. In march I came down with shingles (horrible pain). Two months later I had it again (sick all the while in between with every passing illness). In june I had a horrible sinus infection thing (maybe flu), I made lobster for my husband while I was recovering and had an anaphylactic reaction to it. Went to the doc to get tested, and had anaphylaxis from that. I had recurrent reaction 4 hours later when the meds wore off, then again in walmart days later from no known allergen. They put me on steroids, which took 6 weeks to taper off of and I was so sick I couldnt hardly do anything the whole time. I have had shingles twice again since. Every three weeks I get sick as a dog. I have this recurring illness no one can explain. Here are my symptoms

    -Swollen glands (esp on the right side, and my face swells on the right side when I sleep)
    -Ringing in my right ear, which comes and goes
    -Extreme fatigue, I am falling asleep sitting up when I slept great lastnight!
    -Stress intolerance
    -Tight lungs, I feel like I am having a constant mild asthma attack
    -Wierd symptom, but the asthma attack thing and coughing happens worse just before every bowel movement.
    -Joint pain, most especially wrists and knees. Much worse when I am tired.
    -Muscle aches, mainly lower back and legs
    -Random low grade fevers (99.0-99.6 and Im normally in the 97.’s)
    -Panic attacks (which I have never had before all of this)
    -Skin flushing
    -Pain where my liver is, and it is very tender to palpation
    -Chest pain, bilateral. Only prominent when all of my glands swell (esp inguinal glands which make it difficult to walk when they hurt so bad)

    I currently have all of these, but I now also have developed this skin rash I have had for two weeks. It looks like measles or roseola, but is not either. My primary care doc doesnt know what it is.

    Here are my labs
    CBC, CMP are fine, all within limits
    ANA neg x 3 checks
    Urine HIAA normal, but chromagranin A 86, then recheck 61.
    Rheumatoid factor of 11, normal is below 10. But most people don’t have it at all.
    All other autoimmune labs are normal
    Serum tryptase (for mast cell disorders) is normal
    Halter monitor shows PAC’s and PVC’s, but I was cleared for cardiac
    Lung function tests shows 9% improvement with meds, indicating bronchospasms
    Labs are still out for lyme disease and chronic mono

    My mom has Sjogren’s, which they said is a big possibility for me. But the rheumatologist just blew me off and told me to come back in a couple of years so my labs will be more indicative. Frustrating.

    In between these spells, I feel about 90%. Not much really bothers me and I have tons of energy, as I have my whole life. But every couple of weeks I am convinced I am dying of something. I am miserable, and it is really effecting my life. Then it goes away and I am okay. Someone tell me they have been through this and survived!!!
    By the way, the specialist I have been to include
    my primary care doc
    2 allergy specialist
    an endocrinologist
    a rheumatologist
    a cardiologist
    I am asking because they are stumped

    • ANSWER:
      A lot of people have been through this (or similar) and survived.

      Sounds an awful lot like Lyme disease. But the test they gave you (the ELISA) may well come back negative–because that test is highly unreliable, and often comes back negative, even when the person most definitely has Lyme disease.

      Recommend you read up at the following websites and see if anything here rings a bell for you:

      Good sources of info about Lyme disease:

    I have an undiagnosed condition and need help!?
    I am a 20 year old female who has been having stomach problems for the past year or so, and it has gotten much worse in the past six months. The symptoms are now starting to affect more parts of my body, and the pain can be debilitating and is affecting my schoolwork. I was tested for thyroid issues and Celiac, but both were negative. I also went to the ER for abdominal pain a few weeks ago, but that didn’t turn up any new results.

    Here is a list of symptoms:

    Digestive symptoms – abdominal pain (sometimes crampy and all over, sometimes very sharp in right upper abdomen or left lower abdomen, sometimes made worse coughing or sneezing), LOTS of diarrhea, undigested food in stool almost every day, sometimes fat or mucus in stool, loss of appetite, lots of extreme bloating, some nausea/heartburn/dry-heaving, sometimes foods taste very different than they should (ex – candy tasting extremely acidic, milk tasting like sushi, plain white rice tasting nutty)

    Skin symptoms – I get a red skin rash almost every night or afternoon. It’s itchy, not raised, and not dry. It’s not related to any contact allergy or physical activity. Sometimes, it seems to happen more often or with more severity when I feel really warm or cold. My hair has thinned significantly in the past year, and I’ve started getting coarser hair elsewhere on my body (arms, face). My skin feels itchy most of the time.

    Nervous symptoms – extreme fatigue/malaise, depression/anxiety, headaches, trouble concentrating, photophobia and phonophobia, increased sensitivity to cold and heat, numbness in fingers

    Other symptoms – occasional low-grade fever, muscle weakness/pain, joint pain/swelling, easy bruising (once I got a bruise from the elastic band on my sweatpants and it wasn’t tight, another time on my arm from holding a package – the bruise was in a line from where the package was resting against my arm), I had some very mild jaundice and green-tinted urine at one point. I’m anemic and have high liver function according to the most recent tests. I don’t drink, and I don’t take any drugs unless they are prescribed (I deal with headaches by drinking water and resting). Small doses of Lortab helped relieve many of the digestive symptoms (prescribed by the ER). Diseases that have come up with my doctor are: lupus, Crohn’s or ulcerative colitis, IBS, Celiac (apparently false negatives are common?), and diverticulitis. Also, gallstones and pancreatic cancer were suggested, but less likely. We are pretty sure it’s autoimmune.

    I’m sick of being sick, and am reaching out for help in every place possible. I would love any suggestions or ideas, questions to ask my doctor, tests to request, warm thoughts, or stories (if you had a similar illness and got a diagnosis or found a way to manage the symptoms). I’m seeing my doctor next week, but because I’ve already gone through two series of tests, I want to be more prepared this time to help lead to a diagnosis more quickly. Thanks in advance!

    • ANSWER:
      You have a lot of symptoms that could indicate a variety of problems. Celiac Disease, possible intestinal obstruction (Intestinal carcinoma, lymphoma), bruising is indicative of a bleeding disorder such as Von Willebrand disease or leukemia. Upper right quadrant pain indicates gallbladder disease, especially if fever and nausea are present also. Some of your symptoms are also those that present with kidney disease and diabetes so you have a real jungle of symptoms which has a tendancy to lead me back to Celiac Disease because …

      Celiac Disease is an autoimmune disorder which can present with an amazing array of symptoms, Gastrointestinal (cramps, pain, bloating, fatty stools, nausea, vomiting), Neurological (tingling, numbness, nerve pain, fatigue, depression and more) and so it is just frustrating for people who have it yet have not been diagnosed plus false negative tests are common. The definitive diagnosis is based on a positive biopsy of the small intestine. It’s not uncommon to have a false negative blood test yet have a positive biopsy.

      If you had maybe thought you had Celiac Disease and went on a gluten free diet before being tested that could have created a false positive and it may create a false biopsy if you have been on the gluten free diet for anytime allowing your small intestinal cells to heal and the villi to re-establish. However that doesn’t sound likely that you have adapted the diet because you said you are still experiencing symptoms even though some people with refractory Celiac do not see a reversal of symptom via diet.

      If it were me I’d ask the doc to re-test for CD (blood work) and also do stool fat, total protein, albumin, calcium, vitamin b12, autoantibodies, vitamin d, vitamin e, CBC, CMP.

      Oftentimes Celiac Disease causes malabsorption (reason for fatty stool) and this in turn creates vitamin deficiencies within the fat soluble vitamins such as d, calcium, vitamin k. b12 and so forth. It also causes anemia in many people and a host of other symptoms and complications because (via autoimmune response) it can attack your organs such your heart, lungs, liver, kidneys and pancreas (autoimmune response) thereby creating symptom from those sources as well.

      Celiac Disease can also cause lactose intolerance (nausea, vomiting, diarrhea in severe cases) and so this complication could be a portion of your symptoms.

      I would suggest you keep a very concise diary of your symptoms, including when they occur (time, date, etc…) and of course exactly what they are. Note what you eat daily so that you can correlate your food intake with symptoms (note whether symptoms appear immediately after, within hours, or even a day or two after ingestion). Be as accurate as possible and by this I mean if you chew a stick of gum, write it down because …

      You’d be amazed how many products we eat contain wheat, barley or rye (sources of gluten) or are processed with wheat, barley or rye products. Even spices can contain wheat and wheat derivatives that contain gluten. If you drink wine the oaken cask it was probably aged in most likely was treated on the inside of the cask with a wheat paste to prevent leakage. That paste leaches into the wine and guess what? If you have CD you will most likely suffer intestinal damage.

      Of course I am not saying you have Celiac Disease. You may not have it at all. You may have something else entirely such as cancer that could present with a myriad of strange symptoms or it could be a combination of gallbladder disease (pain, nausea, vomiting, diarrhea, fever, jaundice are all possible symptoms) and kidney disease. Now, don’t let what I write frighten you, simply get your doc to rule various possibilities out by doing the appropriate tests.

      I wish you better health :-)