Abnormal Liver Function Test

That is the perception being acultivateda here. Colon Cancer Statistics 2009 However, after reading medical literature on this issue, it came as a shock to know that one does not necessarily have to die if one does not undergo chemotherapy. The perception I had then was without chemotherapy, colon cancer patients would die -- if not all of them, at least a great majority of them. But research data does not support that perception. Let me highlight two research papers for your reading.

Dr. Charles Moertel and colleagues of the famed Mayo Clinic, advocated the use of 5-FU + levamisole for colorectal patients. They showed that this concoction is more effective than using 5-FU alone. Based on the data of 929 patients with Stage 3 colon cancer, they presented their report in the Annals of Internal Medicine, 1 March 1995, Volume 122: 321-326 ( Fluorouracil plus Levamisole as Effective Adjuvant Therapy after Resection of Stage III Colon Carcinoma: A Final Report) as follows:

1. Out of the 315 patients who did not receive chemotherapy 177 of them, i.e. 56 %, suffered recurrence.

2. Out of the 304 patients who received chemotherapy, only 119 or 39 %, suffered recurrence.

3. Out of the 315 patients who did not receive chemotherapy 168 of them, i.e. 53.3 %, died.

4. Out of the 304 patients who received chemotherapy 121 or 39.8 %, died.

5. The side effects of fluorouracil plus levamisole were: nausea, infrequent vomiting, stomatitis, diarrhea, dermatitis, fatigue, occasional mild alopecia and neurotoxicity.

6. Approximately half of the patients had hematologic depression that was usually limited to mild leukopenia.

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7. Forty percent of patients had abnormal liver function test results during the course of the therapy. Their toxicity were reflected in elevated alkaline phosphatase levels (which peaked approximately 7 months after onset of therapy), elevated aminotransferase (AST) levels, and elevated serum bilirubin besides causing fatty liver.

From the above data it is clear that chemotherapy reduced recurrence by 17 % and reduced death by 13.5 % but not without side effects which are often brushed off as insignificant.

Similarly Wolmark et al. (Postoperative adjuvant chemotherapy or BCG for colon cancer: results from NSABP protocol C-01. J. National Cancer Inst. 1988. Vol: 80:30-36), showed that a mixture of 5-FU + semustine + vincristine also did a good job. Let us look at the data presented below:

A total of 1,166 patients who had undergone surgery for Duke's B and C colon cancer were divided into 3 groups and given the specified treatments. The results of the study were as follows:

1. 59% of those who underwent surgery only (as control group) survived after 5 years.

2. 67% of those who received 5-FU + semutine + vincristine survived after 5 years.

The results demonstrate that the use of 5-FU + semustine + vincristine after surgery for Duke's B and C colon cancer provided higher rates of 5-year survival. Leukemia has been observed in 3 of 479 patients who had received semustine.

Take note that the REAL benefit of chemotherapy in this study can be seen in 8 % of patients only. Also after 5 years, 59% of patients were still alive even without chemotherapy. The question we may want to ask is: awhat if they had undergone chemotherapy?a I expect almost all or a great majority of them to be alive at the end of five years. No, the data shows only 67% of them survived. This is another shocking truth -- even if one were to undergo chemotherapy, research shows that 33% of patients still die from colon cancer.

One doctor told his patient that taking herbs and getting well is a matter of luck. Now, what about chemotherapy? Chemo-patients probably need just as much luck?

The difference of five-year survival between chemotherapy and no chemotherapy group is only 8% or 13.5 % (based on work in Mayo Clinic). Chemotherapy is proven to be beneficial by only a slim margin. Indeed, from the academic point of view, the result is statistically significant. This would please the statisticians and the scientists, but I am not sure if it pleases cancer patients at all. I believe this is not what patients (especially those in the poor developing country) are looking for. They are seeking for a REAL cure (not a MEDISAL CURE either!). If this is not possible, at least they expect a much greater chance of achieving it. I wonder if 8 % or 13.5 % benefit is good enough?

Chemotherapy causes severe side effects in most patients. It is not like an aant-bitea as one oncologist would tell some patients. With only 8 % or 13.5 % difference, is it worth the gamble?

One question comes to mind: Can this slim margin of 8 % or 13.5 % not be achieved by some other non-invasive or non-toxic means? For example, does it ever occur to people that by just a change of diet or taking of herbs, perhaps we can also increase our chances of healing colorectal cancer and the result could be better than chemotherapy? In my future articles I shall present various case studies to show that indeed this hypothesis is valid and has merit -- herbs and change of diet and lifestyle can prolong meaningful survival better than chemotherapy!

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Frequently Asked Questions

  1. QUESTION:
    Had an abnormal liver function test result?
    Just curious what to expect, i have an appt. tomorrow with my dr., but i don't know what can cause an abnormal test result. any answers plz?

    • ANSWER:
      A host of medications can cause abnormal liver enzymes levels. Examples include:

      Pain relief medications such as aspirin, acetaminophen (Tylenol), ibuprofen (Advil, Motrin), naproxen (Naprosyn), diclofenac (Voltaren), and phenybutazone (Butazolidin)
      Anti-seizure medications such as phenytoin (Dilantin), valproic acid, carbamazepine (Tegretol), and phenobarbital
      Antibiotics such as the tetracyclines, sulfonamides, isoniazid (INH), sulfamethoxazole, trimethoprim, nitrofurantoin, etc.
      Cholesterol lowering drugs such as the "statins" (Mevacor, Pravachol, Lipitor, etc.) and niacin
      Cardiovascular drugs such as amiodarone (Cordarone), hydralazine, quinine, etc.
      Anti-depressant drugs of the tricyclic type
      With drug-induced liver enzyme abnormalities, the enzymes usually normalize weeks to months after stopping the medications.

      What are less common causes of abnormal aminotransferase levels?

      Less common causes of abnormal liver enzymes in the United States include chronic hepatitis B, hemochromatosis, Wilson's disease, alpha-1-antitrypsin deficiency, celiac sprue, Crohn's disease, ulcerative colitis, and autoimmune hepatitis. Though not as common as hepatitis C, hepatitis B can cause chronic liver disease with persistently abnormal liver enzymes.

      Hemochromatosis is a genetic (inherited) disorder in which there is excessive absorption of dietary iron leading to accumulation of iron in the liver with resultant inflammation and scarring of the liver.

      Wilson's disease is an inherited disorder with excessive accumulation of copper in diverse tissues including the liver and the brain. Copper in liver can lead to chronic liver inflammation, while copper in brain can cause psychiatric and motor disturbances.

      Alpha-1-antitrypsin deficiency is an inherited disorder in which the lack of a glycoprotein (carbohydrate-protein complex) called alpha-1-antitrypsin lead to chronic lung disease (emphysema) and to liver disease.

      Autoimmune hepatitis results from liver injury brought about by the body's own antibodies and defense systems attacking the liver.

      Celiac sprue is a small intestinal illness where a patient has allergy to gluten and develops gas, bloating, diarrhea, and in advanced cases malnutrition. Patients with celiac sprue can also develop mildly abnormal ALT and AST levels.

      Crohn's disease and ulcerative colitis are diseases with chronic inflammation of the intestines. In these patients inflammation of the liver (hepatitis) or bile ducts (primary sclerosing cholangitis) also can occur, causing abnormal liver tests.

      Rarely, abnormal liver enzymes can be a sign of cancer in the liver. Cancer arising from liver cells is called hepatocellular carcinoma or hepatic. Cancers spreading to the liver from other organs (such as colon, pancreas, stomach, etc) are called metastatic malignancies.
      _________________

      Without knowing what levels are elevated & to what degree they are raised, it is hard to say the exact cause. In my case, I once had mildly elevated liver enzymes from taking many Advil to treat a pulled muscle the month prior to my test. Hope this info helps. Good luck

  2. QUESTION:
    Liver Function Test Result - Abnormal?
    I had a routine blood test with my new GP this week and the results have come back that I have an abnormal Liver Function Test Result. I have to go back in a few days time to discuss the results. What does this mean? what is the likely cause? could it be dangerous?

    • ANSWER:
      without knowing which liver function test was abnormal, there are several tests for the liver, and without knowing what the actual result of the test was, no one can answer you. I would suggest that if it were serious, the doctor would not be allowing you to wait "a few days" before seeing you tho.

  3. QUESTION:
    If someone has an abnormal liver function test , apart from quitting alcohol , what else can they do .?
    Apart from giving up alcohol , what else can be done to help the liver recover.

    • ANSWER:
      here are some good things to do in order to keep your liver healthy.
      1. eat less fatty foods
      2. always eat in little instalments
      3. good amount of intake of water

      Hope that helped! -- hope you are ok too

  4. QUESTION:
    Explain the causes of Mr. X's abnormal liver function test results. Explain some of Mr. X's symptoms .........?
    Mr. X has been admitted to the accident and emergency department. He has been involved in a motorbike accident, is unconscious and has leg injuries which will require surgery.
    Witnesses at the scene of the accident told ambulance staff that he did not appear to have proper control of his motorbike and drove headlong into the path of an upcoming vehicle.
    Before Mr. X can undergo surgery for his crushed leg his blood needs to be tested to see if he has any underlying conditions which need to be taken into account before surgery commences. He also shows signs of internal haemorrhaging and may also require treatment for blood loss.
    The blood results have now been returned from the laboratory emergency services and it now transpires that Mr. X has raised blood alcohol levels and was drunk at the time of the accident.
    His hospital medical records have been traced and reveal that Mr. X has been receiving ongoing medical care for liver disease due to alcoholism.
    He has been attending monthly clinics to monitor his liver function.
    Before Mr. X can receive blood products for transfusion they need to be screened. Mr. X will show specific symptoms of liver disease.

    Explain the causes of Mr. X's abnormal liver function test results. Explain some of Mr. X's symptoms of liver disease (such as jaundice and prolonged clotting time). What advice will doctors give Mr. X to improve his prognosis?

    • ANSWER:
      read this, see if it helps:-
      http://findarticles.com/p/articles/mi_m0CXH/is_3_27/ai_n6357652/

  5. QUESTION:
    please help my liver function test was abnormal. do to my drinking. would non alcoholic drinks be ok instead?
    liver function test results wher 80. i'am trying to go to aa but it's tuff to stop drinking. would drinking non alcoholic drinks be ok.

    • ANSWER:
      Why torture yourself...if you drink non-alcoholic drinks, i think it would make you want it more. Stop all together. Just hang in there. Keep going to your AA and stay away from anything alcohol related.
      Good Luck.

  6. QUESTION:
    what does it mean when a Liver function test is abnormal and high?
    my husband had blood test and his LFT was high and abnormal what does that mean.

    • ANSWER:
      It depends on what tests the doctors are
      referring to.
      Doctors usually do blood tests:
      (1) liver enzymes which show if there may
      be damage to the liver cells.
      (2) liver function tests to show if the cells
      of the liver are functioning well to keep the
      body healthy
      (3) viral testing to see if there is a liver
      problem caused by a virus like Hepatitis
      A,B,C,ETC.

      Blood tests are just a hint that there is
      something wrong. There are a number
      of different things that can cause a wrong
      result...some are human error. Doctors
      usually do more than one test to be sure
      of the accuracy of the first one.

      Some of the tests, known to test the liver,
      are not always specific to the liver alone...
      in other words...it may be a problem in
      another organ who also has this same
      enzyme.

      If it turns out that this is a problem with the
      liver.....It usually starts out as the cells
      of the liver becoming damaged. The immune
      system will respond to this damage and
      cause inflammation to develop in the liver.
      This inflammation will cause the liver to
      enlarge in size. If the problem that caused
      it is removed and the inflammation is
      treated, the liver cells may heal.

      Here is a list of some of the things that can
      cause a liver problem: alcohol consumption,
      medications toxification, chemical
      exposure, fatty liver disease, mushroom
      poisoning, biliary obstruction or malformation,
      metabolic disorders, hereditary conditions,
      auto immune disease, viral infections, and
      there are others.

      If the doctor thinks, from his blood work, that
      there is a liver problem...he will examine
      the patient. He usually will place his hand
      in the upper right Quadrant of the abdomen
      and see if he can feel an enlargement of
      the liver. If he thinks he feels this...then
      he will probably do a Ultrasound or Ct
      scan to confirm it.

      As long as it is taken care of early on, there
      is a very good chance for reversal. It is
      only when the liver cells die off that it
      becomes a more serious and possibly
      an irreversible disease like Cirrhosis.

      I hope this information is of some help to you.
      It is very hard to wait and see what really is
      going on.

  7. QUESTION:
    liver function test abnormal liver emzines 80 ui normal betweem 14 & 42. alcohol releated.?
    i do not have cirrossis yet. how close am i . i no i need to stop drinking please help.

    • ANSWER:
      Most likely it is alcohol related. You have to do quite a bit of drinking to get your liver enzymes elevated. Everybody's liver is different so there is no way to know how close you are to cirrhosis. But you are probably at the point now where it is reversible if you quit drinking. If you don't quit, you will probably be on the transplant list eventually.

  8. QUESTION:
    i'am on my 5th day of not drinking due to my liver function test was abnormal. trying to hange in there.?
    liver function test abnormal reading was 80. have been going to aa meetings. just have to stay sober. my ex girl friend wan'ts to cook dinner tonight. just stay sober??

    • ANSWER:
      matter not for 5 day stop drinking matter now to stop for ever .....proved that drinkin can cause cirrhosis etc ..so better to eat well drink lot of juices ,,,,,,,,and eat all but minimal oily things
      ty for askin freee free to ask if any querry

      Dr

  9. QUESTION:
    abnormal liver function test results. Serious replies only please?
    Hi
    My transaminase SGOT is 103 which is very elevated. I have a slight fever but no other symptoms.
    I have a doctors appointment tomorrow morning but would like to know if anyone else has had similar results.
    Serious replies only please cos i am terrified.

    • ANSWER:
      An SGOT or AST result of 103 alone will mean nothing if this is not accompanied by any other abnormal results like your SGPT or ALT, Alkaline Phosphatase, Bilirubin. For the SGOT result to be significantly scary, it should be in levels > 800 or so.
      Take a deep breath. Relax.

  10. QUESTION:
    I recieved my blood test back and it showed an abnormal liver funtion test result?
    What could be the causes of this? My doctor is following up with me within the month, she told me it wasnt anything that we need to worry about dramatically at this stage. What diseases cause an abnormal result in the liver function test?

    • ANSWER:
      There are a number of causes of a liver problem...
      see if any of these apply to you:
      alcohol consumption, medication toxification,
      chemical exposure, fatty liver disease,
      mushroom poisoning, auto immune disease,
      hereditary conditions like the body holding
      onto too much iron or copper,
      biliary obstruction/malformation/infection,
      cardiac/vascular problems, metabolic
      disorders such as the liver not producing
      a certain hormone or handling glucose
      efficiently, cancer/tumors/growths/cysts,
      and there are others.

      No one blood testing is 100% accurate.
      The doctors usually do more than one
      set of tests to determine the accuracy
      because so many things can effect
      the results of these tests.

      The blood tests the doctor does on
      patients for the liver are:
      1) the liver enzymes
      2) the liver function tests
      3) the liver viral tests
      4) the liver cancer tests
      Each of those mentioned have a number of
      different types of tests included under that
      heading. However, if you place...for
      example: "liver enzymes" in your search
      engine...it will give you sites that tell you all
      about them.
      Here is one link I use very often:
      http://www.labtestsonline.org

      Liver function tests is a general term and can
      mean the liver enzymes. There is only one
      specific liver enzyme and that is the ALT test
      as it is an enzyme that is made mostly by the
      liver cells...the other enzymes, such as
      the GGT, AST, ALP are found in other places
      in the body. It takes all of the different tests
      above to detemine a true liver problem unless
      the doctor does film testing like an ultrasound,
      Ct scan or MRI. They usually reserve a
      liver biopsy until they believe someone truly
      has a liver disease...because it is invasive.

      All these causes of damage to the liver cells
      can lead to the disease known as Cirrhosis of
      the liver.

      If the cause can be found and stopped and
      any inflammation that has been developed in
      the liver is treated...there is a good chance the
      problem can be reversed. It is only when the
      cells start to die off and form scar tissue
      in the liver, that there really isn't
      anyway to reverse it.

      Hope this is of some help ...Best wishes

  11. QUESTION:
    liver function test abnormal?
    i was drunk the other night and went into emergency due to heart palpations (extra circuit) and my liver function came back as alt 110 and ast 278 which i was wondering is that because i the alchol was in my system obviously being drunk, because as an alcholic i get frequent liver function test and they have always come back normal the night aftre booze please no comments how alchol is bad i have heard it all before

    • ANSWER:
      An increase in ALT levels may be due to:
      * Acute pancreatitis
      * Celiac disease
      * Cirrhosis
      * Death of liver tissue (liver necrosis)
      * Hepatitis (viral, autoimmune)
      * Hereditary hemochromatosis
      * Infectious mononucleosis
      * Lack of blood flow to the liver (liver ischemia)
      * Liver disease
      * Liver tumor
      * Use of drugs that are poisonous to the liver
      Diseases that affect liver cells increase the levels of AST. However, increased levels of AST alone do not specifically indicate liver disease.
      An increase in AST levels may indicate:
      * Acute hemolytic anemia
      * Acute pancreatitis
      * Acute renal failure
      * Cirrhosis
      * Heart attack
      * Hepatitis
      * Hereditary hemochromatosis
      * Infectious mononucleosis
      * Lack of blood flow to the liver (liver ischemia)
      * Liver necrosis
      * Liver tumor
      * Multiple trauma
      * Primary muscle disease
      * Progressive muscular dystrophy
      * Recent cardiac catheterization or angioplasty
      * Recent convulsion
      * Recent surgery
      * Severe deep burn
      * Skeletal muscle trauma
      * Use of drugs that are poisonous to the liver
      Stop consuming alcohol in consultation with your doctor/ gastroenterologist.

  12. QUESTION:
    Liver function test abnormal. What can cause these numbers?
    I am 34 years old Male. I do not drink, I do take one 81 mg asprine a day sometimes two. I do a mild work out every few days a week. I am overweight 256LBS and I am 6'1'' Had a liver function test done a week ago and the AST of 42UL on a scale of 0-41 and ALT of 73UL on a scale of 0-40. They did a hep test today and HIV as well as repeat Liver function the liver function today is AST 42UL and ALT 83UL. My girlfriend is pregnant and her HIV and Hep test were neg and we are faithful so mine should be Neg also what can cause this.

    • ANSWER:
      I have had abnormal liver tests for the past year, so much so to where they had to do a biopsy to make sure it wasn't some type of cancer. Their other concern was auto-immune hepititis, which is a disease not contracted through sex, nor is it contagious. You may want to look it up on webmd. It ended up being two things in my case: #1- a fatty liver, and #2- my thyroid disease was (and still is) screwing with my liver enzyme levels. You most definitely may want to ask your doctor about the fatty liver and auto-immune hepititis. The fatty liver can be see through just an ultrasound, but the hepititis can only be diagnosed through a biopsy.

  13. QUESTION:
    my doctor told me my liver function test was abnormal?
    the test result was 80 normal is supposed to be 10 to 42. i think he said 80 was ui. i'am not sure but it's double than normal i know that. do to my drinking for about 17 years drink every day. have not for 2 days now. my doctor says i do not have cirrhosis yet. my ?? is how close am i & can i have one beer once in awhile???? please help.

    • ANSWER:
      I have no magic potions to help you stop drinking, but I do have a bit of advice that you would do well to heed. Your liver is the filtration system of your body. When it is overtaxed by your ingesting too much fatty foods, alcohol or medication, it can't keep up. When it can't keep up, it cannot cleanse your blood an you end up with toxemia. If you can't give up liquor, at least do something to counteract the negative impact. To cleanse the liver, you need to eat dark bitter vegetables such as spinach. Ideally, you should drink spinach and kale juice every day on an empty stomach. (That means in the morning about 30 minutes before breakfast. You should also get dandelion tea which is one of the best liver scrubbers there is. Make a big batch of the tea and drink it all day. Make sure it's between meals. You might get a little lightheaded at first so avoid driving. Do this every day for about a month. Then stay off it for about a week. Then resume. If you take it consistently without a break, it stops working.
      Another thing that helps clean your liver is beet juice. This works very well but again, it does make you lightheaded so do not drive after you've had the beet juice. Just sit at home and wait for it to work.
      Chinese oolong tea is good for your liver too. Keeps you thin as well.

  14. QUESTION:
    liver function test abnormal my alt results where 80. i guess normal is between 10-42?
    how close to cirhossis am i???? do to to much drinking alcohol

    • ANSWER:

  15. QUESTION:
    my liver function test was abnormal my ggt was 80 normal is between 10 & 42?
    this is to to much alcohol. i was told it is a mild elvation. i was woundering if i i drank 2 real beers 2 days a week & non alcoholic beers in between would this be ok. i really don't wanna stop drinking but do have some concerns. please if there is a doctor or nurse or someone that knows about ggt & liver please help. thanks erik

    • ANSWER:
      ahhhhh e.cutz... wasn't i clear enough with you ? Two beers or even 3 are allowed for a man ( by the way what's the content in the states of a can or bottle ) because I am referring to bottles... you can drink this qty always when your ggt returns to normal ( this can be in a couple of months ) and don't go binge drinking during weeks ends... 7 or 8 beers a day at week ends can jeopardize your liver more that 2 beers a day simply because your liver can not detox such a huge amount of beers... you should also show me ( maybe thru my email ) how your other liver functions are GGT is not the only one that shows how yr liver is... the other two are AST and ALT .. do you have results for those ? ... WRITE ME IF YOU WANT

  16. QUESTION:
    ive just been told i have to see my gp about results of a liver function test should i be worried?
    i mean im really worried right now, having something wrong with your liver is one of the worst isnt it? can an abnormal liver function be mild? if so would my doctor want to speak to me about it? to be honest im shitting myself, bloody receptionists give you no info whatsoever
    lol is it possible i have hep c? what kind of moronic answer is that?

    • ANSWER:
      Abnormal liver functions can be mild. One thing that comes up a lot in blood tests is elevated liver enzymes. This can be caused by a lot of things, and elevated enzymes is a relative term. One major cause of elevated enzymes is a fatty liver, you can have this condition even if you are not a heavy individual. This can be taken care of by diet and may not need medication. Obviously there are other more serious causes for abnormal liver functions and you would know better than anybody what your risk for those would be. Just know, if it was extremely serious you would have been asked to come in immediately.

  17. QUESTION:
    can i still drink non alcoholic beer when my liver function test was abnormal due to drinking real beer?

    • ANSWER:
      Actually, yes. Your liver function was abnormal due to drinking real beer. I don't know how heavy of a drinker you were, but the alcohol content in "real" beer is more than the small tidbit you'd find in the non-alcoholic beverages. Studies have shown that if people who have liver problems due to alcohol can limit their intake to no more than one beer a day, they will not usually get any worse. However, most people who are use to drinking more than that can't limit it. Thus, enter the "non alcoholic" beer. It would take about 5 or more of these to be the equivalent of one actual beer, so you can drink it. I wouldn't drink more than 4 or 5 a day, just to make absolutely sure the alcohol content didn't build, but you should be OK with drinking some non alcoholic beer if you just want the taste or enjoyment of having a "beer". Of course, if you can give it all up and drink healthier beverages like juices, water, and Gatorade, or make yourself a fruit smoothie, etc, it would be the best thing for you, but I know that giving up something you like to drink is a hard thing for a lot of people to do, so this is the next best thing. Good Luck with it, and I hope your liver functions improve as you stay away from the "real beer"!

  18. QUESTION:
    my liver function test was abnormal. i have not drank in 2 days is it all right just to have one.?
    liver functuion test results where 80. been going to aa meetings but it's hard. one drink once in a while would this be ok

    • ANSWER:
      No. Having one drink puts you right back at square one. As 'just one' can turn into 'just a few'.

      Keep at it, it will get easier.

  19. QUESTION:
    what can i do about an abnormal liver function?
    in my last few blood test my liver function is shown to be abnormal, hardley ever drink alcahol so that isnt what is causing it ? is there anyway i can improve my liver function before my next blood test?

    • ANSWER:
      No one blood testing is 100% accurate.
      Many things can effect the results of these tests.

      There are different blood tests the doctor does
      to check the liver:
      1) the liver enzymes: However only one enzyme
      is specific to the liver itself, because it is made
      mostly by the liver cells and that is the ALT test.
      The other enzymes are made in other organs and
      are used to confirm the ALT result.
      Liver enzymes are used as an indicator of possible
      liver cell damage.
      Liver Enzymes: ALT, AST, GGT, Alkaline phosphates
      2) the liver functions tests should reveal how well
      the liver cells are able to do the functions needed to
      keep the body well.
      Liver Function Tests: Bilirubin, INR, Albumin, Pt. PTT
      3) the liver viral tests: which should reveal if a virus
      has entered the body and is using the liver cells
      to replicate itself: Mostly known as Hepatitis
      A,B,C,ETC. (Mononucleosis can also affect the liver)

      There are many things that can cause liver cell damage:
      alcohol consumption, medication toxification,
      chemical exposure, fatty liver disease,
      mushroom poisoning, biliary obstruction/malformation/
      infection, cardiac/vascular problems, metabolic
      problems, auto immune disease, hereditary conditions
      viral infections like hepatitis A-B-C, parasite infections,
      and more.

      If the cause can be found and stopped and any
      inflammation that has developed, by the immune
      system, is treated...then the liver cells may heal and
      the problem maybe reversed. If it has progressed
      to where the liver cells have died off and scar tissue
      has developed in the liver, then it is irreversible and
      is known as Cirrhosis of the liver.

      All liver patients are told, No alcohol. They should
      not take any medications that are not approved of
      or prescribed by their doctors (this includes over
      the counter, herbs, vitamins, minerals, supplement,
      etc)

      Many times, liver tests will return to normal with the
      next test...if there is not a liver problem.

      I hope this information has been of some help to you.
      Best wishes

  20. QUESTION:
    my liver function test was abnormal ggt where 80?
    is this really a high reading and should i stop or can i cut down on my alcohol cousumpion to one or two a day. please only a doctor or nurse or someone that knows a lot about this stuff. thanks erik

    • ANSWER:

  21. QUESTION:
    my husband SG PT is 95 & bilirubin is 1.4, why liver function test is abnormal?
    we consulted to one GI doctor , he advised to take Tab. udilivin 300mg BID for 3wks

    • ANSWER:
      I'll try to condense my answer and phrase it in simple terms. . This involved a lot of reading materials.

      The normal range of values for ALT (SGPT) is from 7 to 56 units per liter of serum. So his SGPT at 95 is elevated or high.

      Elevations of SG PT, an enzyme found within the liver cells, indicate that the liver cells are either leaky (internal contents are entering the blood) or damaged. A wide array of conditions can cause this problem. For example, viral hepatitis or alcohol can cause elevated SGPT. We know that patients can have elevated liver tests as a result of fatty liver, a condition that does not necessarily mean generalized obesity. Usually fatty liver is not a cause for significant liver problems.

      Lipitor can cause a drug-induced liver damage. Patients taking this medication must be monitored for elevations of liver tests

      Any liver disease or gall bladder disorder, such as gall stones or hemochromatosis( Iron Overload) can present with these findings. A delayed effect of alcohol is possible but unlikely.
      .
      Other causes are:
      Viral hepatitis; A fatty liver• Alcoholic liver disease *Drug/medication-induced liver disease; been exposed to chemicals that damage the liver • Autoimmune hepatitis *Herbal toxicity• Genetic liver disease• Liver tumors ; Heart failure.- and Strenuous exercise

      Normal bilirubin levels are less than 1 mg/dl (milligram per deciliter). So his bilirubin of 1.4 is high.

      When levels become elevated, eyes and skin may turn yellow (jaundice), urine may appear a dark-tea color, and stools may look like light colored clay. Elevated bilirubin, while not the most common abnormality in blood tests pertaining to the liver, is quite obvious on a physical exam, and it is the liver-related abnormality most familiar to the general public.

      A phrase doctors often hear from their patients is, “I can’t have liver disease, I’m not yellow.” People are often surprised to discover that most people with liver disease will never become yellow. In fact, many bilirubin elevations are not even related to liver disease at all.

      Bilirubin metabolism is very complex and consists of many steps. A problem with any one of these steps results in an abnormally high level of bilirubin.

      As it pertains to the liver, an elevated bilirubin level is usually associated with worsening liver disease or with bile duct blockage (cholestasis).

      Some possible causes of a high bilirubin level include the following:
      * Primary biliary cirrhosis• Primary sclerosing cholangitis
      • Alcoholic hepatitis• Hemolysis—red blood cell (RBC) destruction• Drug-induced liver disease• Choledocholithiasis (gallstones in the bile duct)
      • Liver failure or general worsening of liver disease
      • Tumors affecting the liver, bile ducts, or gallbladder
      • Viral hepatitis
      • Benign familial disorders of bilirubin metabolism, such as Gilbert’s syndrome

      While researching I also found the interesting fact. below
      How to really read a blood chemistry:

      Total Bilirubin: (0.4 to 0.6)

      Bilirubin reflects the function of the lymph and spleen system.

      High total bilirubin:

      Indicates thymus demand for the globulin fraction of protein to deal with toxins. This has decreased the hemopoeitic activity of the spleen, put it into a passive phase, and elevated the passive destruction of red blood cells.

      Indicators: Confirmed by low white blood cells and high total iron. Confirmed by low white blood cells and high total iron.

      SGPT: (18 - 22)

      This is the primary Krebs cycle expressant, occurring as the end result of the release of catabolic fats. The SGPT enzyme exists in the serum as a consequence of substances being released by the fatty membranes of the liver sinusoids and the lymphatic ducts. The liver sinusoids store foods, and the lymphatic ducts store toxins.

      High SGPT.

      Indicates that the primary surfactant substance (vitamin A) is not sufficient to hold the nutrient and toxic substances. This means there are free-floating sugars, proteins and toxins.

      I couldn't find the drug udilivin.

      http://www.abcompany.com/docgolob/bloodchemistry2.htm

  22. QUESTION:
    My blood test came back with abnormal liver function but my doctor said it wasn't too serious?
    I had ITP and underwent 3 IVIG treatmengst at 4 Rituxin/Dexamethasone treatments. I also have been getting migraines the past four months and took fiorecet, advil(still taking it with Coedine #4, 4 pills/dose), tylenol(for about 3 months on and off,2pills/dose), excedrin(only for about a week1pill/dose) and Coedine #4(for the past month or so1pill/dose). I also took a steroid for a sinus infection and 4 rounds of antibiotics throughout the 4 month period.(my immune system was a little weak). Is my liver function abnormal because of all of these medicines?

    • ANSWER:
      Its normal for liver enzymes to be elevated when a person is taking medications that include acetaminophen (in Codeine pills) or ibuprofen (in Advil) and you are taking both of these at the same time. There are much better medications than these for migraines - ask your doc about using a different treatment for the migraines.

  23. QUESTION:
    my liver finction test came back abnormal due to drinking real beer.?
    can i drink a non alcoholic beer like o duels wich only has 0.5% of alcohol in it & what would aa think on the matter. liver function test results where 80 normal between 10 & 42.

    • ANSWER:
      you are talking abt ggt in the blood right ? 80 is a little too much but it is not going to jeopardize yr life yet...yes you can still drink non alcoholic beer and even alcoholic but no more than one or twice a day.... for a period, try not to drink at all so the GGT will return to normal... I am italian doctor, trust me.

  24. QUESTION:
    my doctor said my ggt was 80 on my liver function test normal between 10 & 42?
    my liver function test was abnormal ggt was 80 most likely do to alcohol. is this a real high range. & can i drink 1 or 2 beers every other day. waht about non alcoholic beers like oduels. please if your not a doctor or nurse please don't amswer the question i need facts. thanks erik

    • ANSWER:
      This is a mild elevation. Since you can"t live without your liver however, you don't want to damage it in any way. Non alcholic beers are not a problem--go with them.

  25. QUESTION:
    Has anyone ever had a blood test done, and the results showed abnormal liver function? Whats going on?
    I am very concerned about this. I went to the doctor, and she had blood work done, and everything came back normal except my liver function...it says abnormal. Also, it has mild anemia listed on my results. What does this mean and has anyone ever had this happen? I am very concerned, and I could not discuss it with the doctor because the results were mailed to me versus actually talking to the doctor. She'd told me that she would call and explain them, but never did. What could this mean? Could it be serious or does it just happen from time to time? This is a University doctor so I know she's busy, and can't just take time out of her day to walk patients through all their tests, but still this freaked me out. I'm not sure how bad anemia can get but i'm more worried about the liver issue than anemia. I'm trying to get a follow up appointment scheduled with her this week but unsure if it's going to happen. Anyway, does anyone have any info?

    • ANSWER:

  26. QUESTION:
    how long will it take for my abnormal liver to heal so i can drink alcohol again????
    liver function test abnormal. test result was 80

    • ANSWER:
      e.cutz,
      The answer to your question is dependant on the cause of your “abnormal liver.” Alcohol is usually the prime suspect in liver disease. If this is the reason in your case, you would not be wise to continue taking excess alcohol after your liver has recovered. You do not state what reading/result was ‘80’. When a person has evidence of liver disease, very high ALP levels can tell the doctor that the person’s bile ducts are somehow blocked. Often, ALP is high in persons who have cancer that has spread to the liver or the bones, and doctors can do further testing to see if this has happened. If a person with bone or liver cancer responds to treatment, ALP levels will decrease. When a person has high levels of ALP, and the doctor is not sure why, she or he may also order ALP isoenzyme tests to try to determine the cause.
      The true measures of liver function are - Albumin. 3.5 - 5.0 gm/dL: Bilirubin. up to 1.0 mg/dL: Prothrombin (INR) 25 - 41 sec:
      Other markers of liver disease, the liver enzymes, are - ALT. 1 - 21 units/L: ALP. 50 - 160 units/L (normally higher in infants and adolescents) (alkaline): AST. 7 - 27 units/L: GGT. Men--6 to 37u/litre.
      Women under 45--5 to 27u/litre.Women over 45--6 to 37u/litre.
      You will very likely undergo further tests, if your results are considered high, or abnormal.

      Hope this helps
      matador 89

  27. QUESTION:
    hello, I have done a Liver function test and these two came abnormal bilirubin 2.2 and SGPT 70,?
    I dont have any problem and no symptoms have shown. I dont know whether this is seriuos and what can I do make them normal. Pleas help. thanks, cheers

    • ANSWER:
      The one test is posted is a liver enzyme (SGPT). The
      liver cells make different enzymes, when they become
      damaged..then they leak from the cells and go higher
      in the blood.

      The other test you posted is a liver function test
      (bilirubin). If the liver cells are having a problem
      handling the bilirubin, it can go higher in the blood level.

      However, one blood test is not 100% accurate and
      the doctor really cannot diagnose you with just this.
      With the enzymes, many things can effect the results
      of this test...like exercising before the test was done,
      having an intramuscular injection, having a muscle
      injury and other things. The ALT test is more
      specific to the liver than the other enzymes are,
      since it is made mostly by the liver cells...where
      they are made in other organs, also.

      Bilirubin is made from our dead red blood cells.
      It is then taken by the liver and converted into a
      soluble form to become part of the bile. The
      bile flows through tube like structures, known
      as ducts, to the gallbladder first and then to
      the intestines to help emulsify fats we eat
      so they can be digested.
      So, If there are alot of red blood cells dying off or
      too many are being made...this can cause a higher
      level of bilirubin in the blood. Other things that
      can cause it are: Anything that blocks the flow
      of the bile through the ducts: an obstruction like
      a stone(from the gallbladder) or growth, infection
      in the bile ducts, malformation of the bile ducts.
      Or, if the liver isn't able to convert the bilirubin into
      a soluble form.

      Bilirubin is a pigment, meaning it is a substance
      that colors other things (green-yellow, brownish
      color). Bilirubin has to reach a certain level in
      the blood before signs of it show up.
      Patients may see the yellowing of the whites of
      the eye and skin color (best seen in outdoor
      lighting). They may also notice the urine becoming
      darker in color as the kidneys try to filter it out.
      "If "the bile ducts have become blocked, the
      bilirubin/bile doesn't reach the intestines and
      the patient may notice that the stool are
      turning lighter in color and may float on top
      of the toilet water. The bilirubin, being higher in
      the blood can make a patient itchy.
      If a stone was in the ducts, there would
      be discomfort and pain there. However, some
      people can pass small stones.

      Without all your blood tests results, your medical
      background, and any other tests you have done,
      it is hard to determine what may have caused this.

      I can tell you that all liver patients are told, No alcohol
      consumption and to only take medications that are
      prescribed by or approved by their doctors.
      (this includes over the counter, herbs, vitamins,
      minerals, and supplements and others)

      It would be best and wait and see what the next
      tests shows. An ultrasound would show if this
      is a stone, how well the blood flows through the
      liver, and if there may be liver damaged.
      When there is liver damaged, there is inflammation
      that develops that would enlarge the liver and
      can be seen on this test. Inflammation can be
      treated so the liver cells can heal. It is only when
      they die off that a real problem occurs.

      I hope this information is of some help. Best wishes

  28. QUESTION:
    blood test 4 months after having baby shows abnormal liver function and some iron abnormalities what could th?
    4 months after having my baby i went to see GP about stress, she took some bloods and they came back abnormal liver function and some anemia, had repeat and have been asked to see GP again, never had any issues with LFT before am really worried anyone know what it could be?

    • ANSWER:

  29. QUESTION:
    Can Gallstones cause your liver function test to be elevated or abnormal?
    Hello.

    I currently have been suffering heaps with pain in my upper-right-quadrant and have found that my liver enzymes are elevated. The symptoms of Gallstones are:

    ~steady, severe pain in the upper right section of your abdomen that may be felt right through to your back between the shoulder blades. The pain increases quickly and may last from 15 minutes to several hours before subsiding;

    ~nausea and vomiting;
    ~indigestion, flatulence or general discomfort in the abdomen; or
    ~intolerance to fatty foods.

    And i have every single one of them, the Dr even said he thinks i have gallstones. I have had lots of different tests and things and don't have any things horrible like hepatitis or anything, so do you think Or is it possible for (Gallstones) to cause my liver enzymes to raise?

    Thanks a bunch!

    • ANSWER:
      Gallstones can definitely elevate liver function tests. There are other causes for elevated liver tests as you know. Continue working with your doctor to evaluate this. Good luck.

  30. QUESTION:
    Blood test liver function test?
    I had bloods done and the doc phoned me and assured me its nothing serious but hasnt told me yet what it is

    The liver function test came back abnormal but nothing major !

    What could it be I have been on antibiotics between Aug and Sep now on cocodomol and diclofenac could it just be too much drugs ?

    • ANSWER:
      definitely diclofenac, had exactly same problem. don't worry about anything. they just have to watch you for a couple more months thru tests etc. do not worry about anything.

  31. QUESTION:
    What is an abnormal liver function result and could it be a side effect of morphine?
    My husband has been on morphine capsules for over 2 years for pain caused by Ankylosing Spondylitis. Doctors have said pain management is the best we can hope for. But now his liver function tests have come back at 83? Apparently 40 is normal and his is 83. I don't know what this means. We have an emergency appointment with GP tomorrow but does anyone know what this means? They asked him if he drinks alcohol (he doesn't) which led me to think it must be bad.
    He's on morphine, tramadol, celebrex, gabapentin al heavy duty painkillers - could they be damaging his liver? I'm so worried but feel like I can't ask the doctor a million questions with my husband present because I don't want him to know I'm so worried. He can't work and doesn't get any benefits because I work full-time. He's been refused for Disability so he worries about the future a lot and gets depressed a lot. If anyone has any medical knowledge / general advice I'd be very grateful.

    Ps. My husband is only 35 years old and we live in the UK

    • ANSWER:
      You have some wonderful questions. And you may have to tell your husband to be prepared, because you are going to address your questions with his doc. And if he has a problem with that, he can sit in the car.

      You have every right in the world to know what is going on with your mate. Anyone would be worried since your husband has a condition that carries with it very few options for treatment. You wrote this:" I'm so worried but feel like I can't ask the doctor a million questions with my husband present because I don't want him to know I'm so worried."

      I am sure you have your reasons for not wanting your husband to know that you are worried......I personally would be worried, as it seems a normal reaction toward someone you love. And maybe if he had a little idea as to how you are trying to educate yourself about his condition, he may just feel a little better.......

      The liver is a filter and carries with it over 400 functions. EVERYTHING we injest goes through the liver. He is taking a lot of medications. His function shows working overtime.....can ask the doc how to get those values down.

      Any medication we take can wreak havoc on our livers. The morphine, made from poppys, may be having less effect than the gabapentin (anti seizure used for neuropathy and pain, mood), Celebrex (antiinflammatory) tramadol (non narcotic pain for mild to moderate relief). If your husband is feeling some depression, I would expect him to be on an antidepressant as well. (It could be that the liver is being affected by the AS as well).

      I believe you have every right to be worried, and a wonderfully supportive wife......if your husband doesn't know this, he should!!

  32. QUESTION:
    abnormal blood test for liver which fixed itself. then mild monocytes...now fixed and now mild lymphocytosis?

    what is going on? i had a blood test monthes ago and my liver function was abnormal..and then it fixed itself on my next blood test.

    Im 24...then i had a blood test and my monocytes were raised...then i had a repeat and they went down and my lymphocytes are raised...mild lymphocytosis.

    what could all this mean? could it poossible be cancer, HIV or something? im really scared but the doctor just said he is repeating the blood test in 6 weeks. so far im not sick but i had a fever and sore joints before i had my monocytes...so hopefully an infection would raise them? im freaking out tho because on the net HIV or cancer is related to lymph

    • ANSWER:
      It's called Fatty liver your Doctor should

  33. QUESTION:
    Liver function tests come back abnormal..?
    What can this mean? Im panicking that it may be something serious I can't see a doctor until later today. Thanks
    Yesterday before I had my blood test I took 40mg omerprazole, 100mg Zydol and 2 paracetamol. This has all been prescribed by a doctor. Thanks

    • ANSWER:
      Can you share what the exact values are on the tests?

      Do you have any other health issues?

      Do you take any medications (prescribed or over-the-counter) or supplements?

      The acetaminophen (paracetamol) can cause elevations in liver enzyme tests. This depends on how much, how often, and for how long you take it.

      Slight elevations are usually not of concern.

  34. QUESTION:
    liver function test results?
    i need answers please from a doctor or someone that really knows please. my boy friend had a liver fuction test & it came back abnormal. results where AST 80 ui/l & ALT 33 ui/l. can any one tell me how bad this is. he is having a hard time dealing stop drinking alcohol.

    • ANSWER:
      Those results are not that bad.
      It's more of a wake-up call than a death toll.

      If your boyfriend cuts back on his drinking, the levels will go back down.
      If he continues to drink to excess, the levels will continue to climb. And then he really will be in trouble.

      The liver is a remarkable organ with the ability to heal itself. It can absorb a weekend binge and detoxify itself. But if that weekend binge becomes all-day-everyday drinking, so the liver is always pickled, the toxins just keep building and building.

      Think of it like a sponge. You soak it. But then leave it alone and it'll dry out and be fine to use again and again. If you keep it perpetually wet, it'll eventually start to rot.

  35. QUESTION:
    My doctor told me Ive got abnormal liver function, what could this mean?
    I went to docs yesterday regarding something else, and my doctor saw from my last blood test 4 months ago that it shows abnormal liver function, I didnt call back to get results so it has been missed, Ive got to go back tomorro for more blood tests to find out next week, Im a little worried in the mean time, as I have no idea what this means....

    I dont drink alcohol at all, havent done for around 3 years, Im 27

    • ANSWER:
      I'm a bit concerned that no-one followed up your abnormal Liver Function Test results for four months. The fact that you didn't call back for the results is irrelevant.

      It is not unusual for test results to be slightly outside the normal range, it doesn't necessarily indicate a problem. All abnormal LFT results should be checked after about a week. Quite often the "abnormal" result has resolved itself. If the results are significantly abnormal and a repeat test shows no improvement, further investigation is required. If a repeat test shows a deterioration in Liver Function, then urgent investigation and possibly treatment is required.

      Try not to worry about your results, the chances are that the repeat tests will be normal. I do not want to undermine your confidence in your doctor, who I am sure is excellent, but I have seen many "abnormal" LFT results caused by blood being taken following a physical examination. Because I worked in a teaching hospital, most patients had been examined several times before blood was taken. Poking a patient's abdomen is an excellent way to squeeze the liver, thus raising the levels of the liver enzymes in the blood. This change is temporary and harmless as long as the reason for the rise is appreciated. Blood for liver function tests should be taken PRIOR to an abdominal palpation.

      I see, from a previous question that you have answered, that you have IBS. If you have been constipated or had to strain your abdominal muscles at all, or even if you have vomited, the pressure on your liver may have caused a temporary elevation of enzyme levels.

      Ask your doctor why your LFTs have been tested in the first place. GPs do not always explain why they are doing things but, if you ask, they are usually quite happy to tell you what is going on. You could write down any questions you have before you go in, so that you don't forget to ask.

      Good luck.

  36. QUESTION:
    abnormal liver function at 17 weeks?
    im having my second baby and recent test have shown my liver has very abnormal funtioning
    has anyone experienced this before what was your outcome.?

    • ANSWER:
      yes I have I had gaul stones didnt find out till 3 weeks afetr my son was born

  37. QUESTION:
    liver function test results-proteins?
    Hi

    I ve already done a blood test recently and all my liver function is good except the following:

    Total protein 96 (66-84 Standard)
    Albumin 54 (38-50)
    Globumin 42 (33-40)

    I m a bit worried about it, although my family doctor said it is okay.But i still wonder the reason why these data is abnormal. Can you give me some suggestions or advices as how to reduce these datas?

    Looking forward for your reply.

    Cheers
    Khem

    • ANSWER:
      Trust you Dr i think. I have gone through many testings and treatment and am familiar with LFT. Believe me your results are so close to "normal" margin its is OK. Our bodies fluctuate and chances Next time you have test it will be a little different. Though I am not DR and if you are concerned seek second opinion.

  38. QUESTION:
    What does "abnormal liver function" mean?
    Okay, I had tonsillitis very badly a couple of weeks ago so the doctor gave me a blood test to find out if it was caused by glandular fever. I phoned up earlier today to get the results and all they told me was that i had an "abnormal liver function" and that i should make a phone appointment with a doctor as soon as possible.

    I just need to know what they meant by this and whether to be worried or not, i have a tendency to worry too much!

    Thanks in advance
    The default category for this was "cancer"! :O

    How likely is this!?

    • ANSWER:
      the liver plays a huge role when you have an infection of a glandular nature, so one would expect the liver function tests to be somewhat abnormal. They likely said that to make sure you followed up. Not to worry, they don't find cancer with liver function studies.

  39. QUESTION:
    Yellow Stool? Abnormal Blood Test?
    I have had yellow stool for awhile now and recently had a liver function test come back abnormal. my kidney test was fine but my doctor told me to come back in a month for another test. I am also an alcoholic. I havent had a drink in a month and my stool has gotton better a bit more brown but sometimes its still very yellow. Anybody have any incite on this this is scaring the heck out of me. I feel like Im trying everything. I guess Im just lost.
    Wouldnt my stool turn back to normal after a month if it was reversable?

    • ANSWER:
      The yellow stool is a wake up call that you're alcoholism is taking it's toll on your liver. How badly it's damaged will determine your doctor's next coarse of action.

      If it clears up after a month, you may have been fortunate enough to have caught the liver disease at a point where it was at the fatty liver stage, a reversible condition if alcohol consumption is stopped. It will take further evaluation - including a sonogram of the liver to determine if there is any permanent damage. The gold standard is a liver biopsy. This will give a complete picture of the extent of damage to your liver.

      Good for you for quitting drinking over this last month. That's key to maintaining your health regardless of what condition your liver is in. Having watched people die from cirhossis, I can tell you it is something you want to avoid at all costs.

      Good luck to you!

  40. QUESTION:
    abnormal liver test results- what could be wrong and how will they fix it?
    ive been on medication for TB (Rifinah) which i was aware can effect your liver slightly, for almost 3 months, and recently became very ill with them.
    I have been extremely tired, nausious, lost my appetite, and eventually the whites of my eyes became yellow.
    After contacting the TB nurses they sent me for blood tests, the results came the next day and i was told they were 'not good' and i will need a blood test every week because 2 parts of my liver are not functioning correctly.
    im 17, will i have this problem forever and what can be done about it? the nurse didnt tell me the exact problem.

    • ANSWER:
      With tuberculosis, it can move from the lungs to the liver.
      It may not cause permanent damage when it does this...
      however, the use of certain drugs needed to combat the
      tuberculosis can cause liver cell damage. [ All prescribed
      medications should "never" be discontinued without the
      doctors authorization.}

      Rifinah is also known as Rifampicin/isoniazid.

      It would be wise to have an appointment set up with a
      gastroenterologist or hepatologist to check your liver.
      He can work with your other doctors to be able to place
      you on a medication that is less hard on your liver and
      can check your liver to be sure it will be fine through
      this treatment and see if there is any liver cell damage.

      I'm going to give you a link that may be of some help
      to you in making this decision. You just have to click
      on it:
      http://medind.nic.in/ibr/t06/i4/ibrt06i4p232.pdf

      When the liver cells become damaged, the immune system
      of the body responds to this damage and causes
      inflammation to develop inside the liver. The inflammation
      can cause the liver to enlarge in size, which can be seen
      on an ultrasound scan. It is very important that a patient
      is watched very closely when this takes place and a
      determination of treatment should develop through a
      liver specialist and doctors treating the TB.

      I hope this information has been of some help

  41. QUESTION:
    Blood test results and some medical history... should I worry?
    Three years ago, I had a CBC: WBC 3.9 (lymph 46%), hemoglobin 13.0 and hematocrit 36.0%. Only WBC and hematocrit were outside of the normal range, though not by much. I had this test done b/c I skipped 8-9 periods (no other illness, medication, eating disorder, excessive exercise, or undue stress). Even 2 months of progesterone therapy did not work, though it eventually came back on its own.

    Now my new doc says I'm slightly anemic. He did a test on my serum and told me to take 1 iron pill a day. I've been taking them for about a month and haven't really felt any difference (I get randomly depleted, though I can still run long distance). I'm going back for more blood tests in a few months.

    Also, my neck is usually a little tender. I don't mean to sound like a hypochondriac...

    P.S. I had an abnormal liver function test a few months ago; ultrasound normal. Going to repeat that, also. I have microscopic hematuria which they will also check.

    • ANSWER:
      Hi. Reading your question I would say you need to talk with your doctor or get a new one that really satisfy all your doubts. The hematuria needs to be checked and I'm sure they need to rule out more test to be sure there is nothing wrong with you. Being worried about your health doesn't make you a hypochondriac. If you worry without reason... that would be another issue... You need to see a doctor to clarify everything and then you can relax knowing you are healthy!!!

  42. QUESTION:
    Do they check liver function before doing general anesthesia?
    I ask because my mother had brain surgery 2 weeks ago. Surgery went fine, she recovered quickly and is back to her normal self. A couple days ago she went in for her usual meds check where they do blood tests. Her liver function levels were off the charts. I always assumed they did a liver function test before surgery so I'm trying to confirm this. We can't imagine what would cause her liver test to be abnormal if it was normal just a couple weeks ago. She was sick the night before her blood test, vomiting and diarrhea but was fine by morning. Could that have affected the test?

    • ANSWER:
      well i guess my first question is did they do a blood test just before surgery? if they didn't then no they didn't check liver function. if a blood test was done just prior to surgery then they should have checked liver function.

      another thing that i'm thinking is if she still has her gallbladder it may be acting up.
      your gallbladder takes in bile from your liver and helps digest food. when your gallbladder is not functioning right your liver function will be out of wack. and gallbladder problems can make you ill and throw up especially during the night and after fatty or greasy foods.
      if she is having pain in the upper right part of her stomach and/or pain in her back near her right shoulder blade then you should take her to see her dr to check her gallbladder.

  43. QUESTION:
    I have mild cirrhosis of the liver, What is my prognosis?
    I was admitted to hospital with a gastric bleed in January this year, they were not sure where the bleed was. I had two esophageal varices banded and are now gone.I also suffered hepatic encephalopathy, ascites and oedema which have all cleared up now. An ultrasound test showed some liver scarring and liver function tests were still abnormal after 8 months. I am not in end stage liver failure but what is the prognosis?

    • ANSWER:
      You don't say what has caused your cirrhosis which is very important for me to answer your question correctly. I don't believe you have mild cirrhosis from what you say about your symptoms. My liver was 90% destroyed with cirrhosis and I didn't have all your symptoms so I think your liver disease is more advanced than you think. This is my own personal opinion, but I would say your prognosis wasn't good and you will eventually need to get a transplant. When you have mild cirrhosis, it is asymptomatic which means you have no symptoms that anything is wrong. Since you were able to get your symptoms under control with treatment and meds, that means your cirrhosis is "compensated" which is stage B of cirrhosis. When the treatments and meds start to not work so well at controlling symptoms, that means it is "decompensated" and total liver failure is near.

      I had cirrhosis and even with my liver being 90% destroyed with scar tissue, I still was able to control my symptoms all the way up till my transplant. I had primary biliary cirrhosis which means my autoimmune system attacks the bile ducts inside my liver. I had varices banded too and got them checked every 3-6 months. I never had enceph. By the time any symptoms appear physically with cirrhosis, the disease is usually pretty far advanced.

      If your cirrhosis is caused by alcohol abuse, then you need to stop drinking ALL alcohol. If you don't, drinking on top of having cirrhosis no matter how mild it might be is like adding gasoline to a fire. It only gets worse much quicker.

  44. QUESTION:
    Liver function question (in regards to blood test)?
    I had a hernia operation July 7 2008. Pre-operation blood test were fine. I took ketorolac for about a week after the surgery. (only thing I can think of that may have caused it) I went for a physical 3 weeks later (July 31st) and blood test showed liver funtion test was abnormal. I dont know what they were but it looked like 4 catagories. All the other items on the blood test were good. Hepatitis was also negative. 37 yrs old social drinker in good shape. Could this be from the that medication 3 weeks prior or something minor and could it then return to normal? Dr. told me to come back in 3 months to re-test but told me not to let it bother me.

    Thanks in advance
    Mike

    • ANSWER:
      I'm no expert, but I do work in the medical field. I'm also usually pretty good at finding things online...

      It could be the Ketorolac. According to Wikipedia, "Ketorolac also elevates liver protein levels."

      Since liver tests include liver enzymes, elevated liver protein levels due to your medication could classify as "abnormal" in this case. Since I'm sure your doctor knows this, that would explain why he/she is not too concerned.

      Hope this helps.

  45. QUESTION:
    abnormal liver function?
    im 18 year i drink alchol once a week (weekends, maybe 15-20 pints) i had a blood test 2 weeks ago and i recived a ltter saying my liver is fuctioning abnormally.. thats all it say's and i need tyo go for another test in 3 months
    what could it be ?
    can i drink alchol ?
    is it liver desiese ?

    • ANSWER:
      Alcohol is the number one cause of liver
      disease. It would be best to stop drinking
      immediately. Some people can drink all
      their lives and never have a problem...other,
      who are sensitive to alcohol, doesn't take
      much to cause a problem.
      Anyone who finds out that they may have
      a liver problem are told right away:
      no alcohol. They are also told to inform
      the doctor of all medications taken:
      over the counter drugs, street drugs,
      herbs, herbal teas, vitamins, minerals,
      supplements, and medication prescribed
      by their other doctors. The reason for
      this is that all medications go through
      the liver first to be broken down before
      they go to the rest of the body. If someone
      is on any medication and has a liver problem...
      it may have to be adjusted according to how
      well the liver cells are functioning and also
      because some medication are harder on
      the liver than others ones are. It is best
      to take only medication prescribed or
      approved of by your doctor now.

      The doctors do different blood tests to
      see how the liver is doing:
      The liver enzyme test show if there may
      be damaged to the liver cells.
      The liver function tests show how well
      the cells are functioning to keep the body
      healthy
      Viral testing to see if it may be a problem
      with the liver caused by a virus, Like
      Hep A,B,C, etc.

      Only the doctor would be able to tell
      from your blood tests if this is definitely
      liver related. However, it is best to start
      early on in stopping anything that you
      think may be a cause. If the cells of
      the liver become damaged, the body's
      immune system responds to this and
      can cause inflammation to develop
      in the liver, also. This inflammation has
      to be treated and the cause removed or
      it can lead to death of the liver cells and
      an irreversible disease known as
      cirrhosis of the liver. If treatment is
      started and the cause is removed, there
      is a good chance it can be reversed before
      it gets to this stage.

      No one blood test is 100% accurate. It is
      good that they want to do more testing to
      be sure.

      I hope this information is of some help to you.

  46. QUESTION:
    Abnormal liver findings-What does long wait to see specialist indicate in terms of seriousness?
    So...a family member went to doc after several liver function tests came back high and sonogram showed "abnormal liver findings".

    He has been vomiting almost daily for two months and is a heavy drinker. Doc referred him to gastrohepatology. Their office told us that it would be a two-month wait. When we asked why so long, they said their screeners studied the lab results and felt it was safe to wait for two months..however they won't tell us anything else.

    If it is "safe to wait two months"...does this mean the findings indicate that things aren't very serious? Or could it be that it is serious and two months at this point won't make a difference in someone's physical outlook?

    We are kind of playing a guessing game here but cannot get more info. We just don't get what this long wait means. What if the findings turn out to be cancer? Could this mean they already know it isn't cancer...or otherwise they would get us in soon?

    Sorry..I know this is all speculation but I'm just looking for experienced opinions. Obviously I realize no one knows the actual answers here.

    Thank you in advance.

    • ANSWER:
      I will first try to tell you what might be happening:
      The doctor took blood testing:
      1)The liver blood enzymes were high...this means that the liver cells may be damaged. These enzymes are made in the liver cells, any damage to them can cause them to leak out.
      [Tests: ALT,AST,GGT, Alkaline Phosphatase]
      2)The liver function blood tests would give the doctor an idea of how well the cells are able to do the functions needed to keep the body well. Cells do 500 plus functions for the liver.
      {Tests: Bilirubin, INR, Albumin, PT, PTT}
      3)The liver viral tests to see if a virus has entered the body and is using the liver cells to replicate itself.
      This is an example of what those blood tests mean.

      If the liver cells are damaged, the immune system of the body would respond to this damage and cause inflammation to develop inside the liver. This will cause the liver to enlarge in size. This, then becomes more serious. If the cause would be stopped and the inflammation is treated...the liver cells may heal and the problem can be reversed. It may take some time for this to take place. {Alcohol is only one of maybe 50 things that can cause cell damage in the liver}.

      If this does not take place..the liver cells will start to die off and form scar tissue in the liver. The scar tissue then blocks the flow of blood through the liver on its way back to the heart. It also blocks the flow of blood to the other liver cells (even the ones that try to regenerate) and they will die off also [lack of oxygen and nutrition].
      There is no turning back then...it becomes a progressive disease known as Cirrhosis of the liver. The doctors can try to slow it down and the patient can help by stopping the cause...
      Liver failure is the beginning of Cirrhosis. It means that the cells are dying and the functions that the liver does, as a whole is deteriorating. As more cells die off, the less functions are done. The liver then will start to shrink in size and take on a hard texture. It will keep going until there is complete liver failure.

      The doctor who referred you to them, could of requested an earlier appointment and had it set up for you. I would call and tell them you would like this to be done. You could contact this office, where they told you to wait, and tell them if another patients cancels..you want them to contact you..so he can be seen. Or you could request to find another specialist who would take you earlier.

      All liver patients are told, NO alcohol. They are also told not to take any medications without the doctor approval or a prescription from him. (this includes over the counter meds, vitamins, minerals, herbs, supplements, etc) Most medications go through the liver first, to be broken down, before going to the rest of the body. With cell damage in the liver, the medications have to be adjusted accordingly and also monitored closely.
      No one who is sick, should be around him. Wash hands often, use purell over times. Avoid open salad/dessert/food bars that people can sneeze or cough into. Use disinfectant wipes on shopping cart handles, door knobs, light switches, etc. Becoming sick with liver disease will weaken the body more and make him take more drugs.

      The best test to have done to see how far advanced this disease is, is a liver biopsy. Looking directly at a specimen is much better than just films (pictures) of it.

      He should have documents made up so someone can talk directly with his doctors. Having an advance directive or power of attorney signed by him...would give even his family members access to information that the doctor might withhold otherwise. Privacy laws are a royal pain!!

      He is allowed to have a copy of any lab work he has done. At the lab, all he has to do is sign a form and they can fax him a copy of his results when they also fax the form to his doctor. To look up any lab work he might have, here is a site: http://www.labtestsonline.org

      Here is one for an advance directive:
      http://www.caringinfo.org/stateaddownload

      Here are some for learning more about Cirrhosis:
      http://www.medicinenet.com/cirrhosis/article.htm
      http://www.mayoclinic.com/health/cirrhosis/DS00373

      Here are a couple that explain the process of transplantation:
      http://www.surgery.usc.edu/divisions/hep/patientguide/index.html
      http://www.transplantliving.org/

      If he has trouble going off the alcohol...the doctor can place him into a detox program at the hospital... they would give him drugs there to lessen the symptoms of coming off the addiction. If this is Cirrhosis and he has to have a transplant...he would have to be detoxed from the alcohol for a period of six months prior to be listed for a donor organ.

      This is a Warning: If you see he is throwing up any blood or his throw up has even slight pink streaks or if he is bleeding from his rectum...this is an emergency situation.
      When the blood cannot go through the liver, it backs up into smaller vessels located in the esophagus and rectal areas. These vessels are not used to this amount of blood and pressure...they may have weak spots and balloon outward. They can burst open and the patient can bleed out completely or bleed internally.
      The doctors can band these vessels to stop the bleeding.
      (Portal Hypertension with Varies)
      http://familydoctor.org/online/famdocen/home/articles/188.html

      The best test to have done to see how far advanced this disease is, is a liver biopsy. Looking directly at a specimen is much better than just films (pictures) of it.

      I hope this information is of some help to you. You can go to any site, I posted, by clicking on them. I sure hope they give you a sooner appointment.He is very fortunate to have a family love him so much.
      Best wishes to you

  47. QUESTION:
    Blood tests show abnormal liver functions.....?
    Husband felt dizzy a few times and went to ..docs...took blood tests and results showed low blood pressure but also liver functions to be low, they said it was due to his weight...he is 5ft 10in and 15ish stone, but has a manual labour job and defo doesn't look fat...can anybody relate to this and leave any ideas..Thanks in advance
    the doctor told him to come back in 6 weeks for another blood test, no medicines were given

    • ANSWER:
      my bf had a similar problem over xmas and doc said that his liver function tests may be abnormal due to a viral illness, he had repeat tests done 4 weeks later and they were completely normal again, so dont worry until he gets his 2nd results back

  48. QUESTION:
    will drinking a lot of water rid my liver from alcohol faster?
    liver function test abnormal

    • ANSWER:

  49. QUESTION:
    Liver Function Tests?
    I am over 40 years old and have been drinking alcohol regularly the last 15 years. My Liver Function tests returned with abnormal AST (60) but normal for all others (e.g. ALT = 40). Both have been in 20s last year and the year before. I have had pain in the stomach area / abdomen during the last year usually for a day or two after drinking alcohol.

    Is the condition serious? I may have alcoholic hepatitis. Is it reversible? I searched the Internet and found some good info but most are confusing. Thanks!

    • ANSWER:

  50. QUESTION:
    Recently found a lesion in the low left lob of my liver. Need to worry?
    I have not been feeling well for the past 5-7 months. After many question and answer appt's with my Dr. I started having weekly blood tests to check various things. My erythrocyte sed rate and c-reactive protein were more than double the reference ranges. I also had abnormal liver function tests. After ultrasound I was told I had a lesion and needed a CT scan to determine whether or not it was something to worry about, which in fact I had done today. Although I have high hopes of benign findings I can't help but factor in my constant sick feeling, flu like, pain when pressure is put on my abdomen and my grandmother passing from liver cancer. Anyone that can give me some helpful statistics would be greatly appreciated.
    No biopsy, as of yet.

    • ANSWER:
      The one thing I can say is : Do not put the carriage before the horse.
      Wait and let your tests get done, its a big worry but you can do it. Are they planning a biopsy ? Once you find out what it really is its hard to have a settled mind, I know , been there. But take things one day at a time. Always wish for for the best. And think to yourself, How strong am I ? Even if there was something, science and the medical field have come so far and the fact that you seem to have caught it in the early stages( because it has not taken over your kidney, only a lesion) then you will get through this with time, and with hope and with loved ones by your side. Be strong for you. I wish you only the best.